CD1 and lipid antigens: intracellular pathways for antigen presentation.

نویسندگان

  • J Jayawardena-Wolf
  • A Bendelac
چکیده

Recently, different members of the CD1 family of MHC-like molecules have been shown to sample different intracellular compartments to present lipid and glycolipid antigens to T cells. Emerging models suggest that CD1 may have evolved to monitor the integrity of membrane lipids and/or to present microbial lipid antigens to both alpha beta and gamma delta T cells.

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عنوان ژورنال:
  • Current opinion in immunology

دوره 13 1  شماره 

صفحات  -

تاریخ انتشار 2001